Tumour necrosis factor-related apoptosis-inducing ligand (TRAIL) is a molecule belonging to the tumour necrosis factor (TNF) superfamily. In humans, two TRAIL receptors (TRAIL-R1 and TRAIL-R2) and in ...
Apoptosis has an essential role in embryogenesis, adult tissue homeostasis and the cellular response to stressful stimuli, such as DNA damage, hypoxia or aberrations in cell-cycle progression 1.
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