K. pneumoniae is frequently the source of hospital-acquired infections and, due to the widespread use of antibiotics in these settings, has also acquired numerous resistance genes. In fact, over ...

Upper: Antibodies recognize and bind to their specific target on the surface of cells. In complement-dependent cytotoxicity (CDC), complement binds to antibodies and forms a membrane attack complex ...

Dysfunction of the complement system plays an important role in the pathogenesis of renal diseases. Complement inhibitors, such as C5 inhibitors, have shown efficacy in clinical trials, but may no be ...

Antibodies are one of the most specific tools for the detection and capture of molecular targets­­. The right antibody can play a key role in revealing the presence, quantity, dynamics, and even ...

Lipids are the fatty molecules that make up cellular membranes, creating a protective barrier that regulates what enters and exits the cell. Until recently, scientists believed antibodies couldn't ...

A simulation of a broadly neutralizing antibody (dark and light blue chains) binding to the HIV-1 viral membrane. The membrane comprises lipids and cholesterol (gray sticks) and phosphates (orange ...