A genome-wide CRISPR study maps 331 genes essential for early brain development, identifying PEDS1 as a new ...
Which genes are required for turning embryonic stem cells into brain cells, and what happens when this process goes wrong? In ...
By editing thousands of genes in mouse stem cells, the scientists identified a list of over 300 that are crucial for neural differentiation.
A study led by Dr. Li Chuanyun from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences (CAS) has revealed how recently evolved human-specific genes—critical for ...
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Jumping genes reshape cancer genomes through 3D chromatin interactions
Scientists at St. Jude Children's Research Hospital have revealed previously unappreciated roles for the retrotransposon LINE-1 in shaping the cancer genome structure and regulation.
The team of Professor Christof Niehrs at the Institute of Molecular Biology (IMB) in Mainz, Germany, has discovered that a DNA modification called 5-formylcytosine (5fC) functions as an activating ...
A human-specific NOVA1 variant changed mouse vocalizations, potentially providing insights into the evolution of language. Darnell said the switch to the new NOVA1 variant likely occurred between ...
“This is the first detailed study of how and where ORC regulates epigenetics and gene expression in human cells,” said Anindya Dutta, Ph.D., leader of the study and chair of the University of Alabama ...
Nucleome Therapeutics ('Nucleome' or 'the Company'), a company tackling the molecular causes of inflammatory diseases through a ...
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