Class II transposable elements transpose via an internally encoded transposase acting on the flanking 5′ and 3′ terminal inverted repeat (TIR) sequences and adjacent DNA that may include subterminal ...
A variety of mutations in lentiviral vector expression systems have been shown to generate a non-integrating phenotype. We studied a novel 12 base-pair U3-long terminal repeats (LTR) integrase (IN) ...