Researchers at the UCLA Jonsson Comprehensive Cancer Center have identified a new role for a protein called extracellular signal-regulated kinase (ERK) in a pathway activated by interferon-gamma that ...

A recent study led by Associate Professor Takuya Yamamoto and Researcher May Nakajima-Koyama has revealed that maintaining a delicate balance between interferon-gamma (IFN-γ) and extracellular ...

Researchers in Japan showed that a unique neutrophil subset, characterized by type II interferon signature genes (T2ISG), along with elevated levels of interferon gamma in the blood, can predict the ...

Scientists have discovered how a mitochondrial mutation rewires immune function in a model of inherited primary mitochondrial disorders, which often lead to severe disability and death. They have ...

A new research study from scientists at the Massachusetts Institute of Technology (MIT), Dana-Farber Cancer Institute, Harvard Medical School, and elsewhere explains one of the mechanisms that ...

Ossification of the posterior longitudinal ligament (OPLL) is a progressive spinal disease characterized by ectopic bone formation in the spine, leading to severe neurological symptoms due to spinal ...

Why does the COVID-19 virus make some people sicker than others? For years, scientists have looked to a critical piece of immune system machinery - known as the interferon pathway - for answers. There ...

CAMBRIDGE, MA -- One of the immune system’s primary roles is to detect and kill cells that have acquired cancerous mutations. However, some early-stage cancer cells manage to evade this surveillance ...

Duke Health researchers found a relationship between immune response and neurological behavior after studying mice with a specific gene mutation, which exhibited signs of ADHD in response to an ...

Researchers found that precancerous colon cells can avoid immune detection by turning on a gene called SOX17, which allows them to become essentially invisible to the immune system. One of the immune ...