MutS is a mismatch DNA repair protein, originally described in Escherichia coli. Mismatch repair contributes to the overall fidelity of DNA replication and is essential for combating the adverse …

MutS is a key enzyme in DNA mismatch repair (MMR) that corrects mismatched bases produced during DNA replication and other biological processes [1, 2]. MutS recognizes mismatches and …

MutS is the bacterial MMR protein that recognizes mispaired bases in DNA (“Mut” is an abbreviation for “mutator” because mutations in the mutS gene cause high mutation rates or a …

MutS is a mismatch repair enzyme from Escherichia coli, expressed in the recombinant form in the same host, which selectively binds DNA fragments containing mispaired or unpaired bases.

UniProt is the world's leading high-quality, comprehensive and freely accessible resource of protein sequence and functional information.

Oct 3, 2022 · Highly conserved MutS and MutL homologs operate as protein dimers in mismatch repair (MMR). MutS recognizes mismatched nucleotides forming ATP-bound sliding clamps, …

Jun 22, 2025 · The human counterparts to MutS are called MSH (MutS homolog) proteins, and the equivalents to MutL are the MLH (MutL homolog) proteins. In humans, these proteins work …

The gene products are, therefore, called the "Mut" proteins, and are the major active components of the mismatch repair system. Three of these proteins are essential in detecting the mismatch …

Apr 7, 2025 · MutS is a regional lesion sensor that specifically recognises mismatches in DNA. It forms a complex with MutL, a weak ATPase that mediates protein-protein interactions during …

MutS, also known as the "mismatch recognition" enzyme, is essential for the DNA mismatch repair (MMR) biological pathway. It recognizes base-base mismatches and small nucleotide …