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  1. SRY gene: MedlinePlus Genetics

    The SRY gene provides instructions for making a protein called the sex-determining region Y protein. Learn about this gene and related health conditions.

  2. Sex-determining region Y protein - Wikipedia

    Sex-determining region Y protein (SRY), or testis-determining factor (TDF), is a DNA-binding protein (also known as gene-regulatory protein/ transcription factor) encoded by the SRY gene that is …

  3. Molecular Mechanisms of Male Sex Determination: The Enigma of SRY

    The human testis-determining gene Sry, a single-copy gene on the short arm of the Y chromosome, encodes a high-mobility-group (HMG) box, a DNA-bending motif conserved among architectural …

  4. SRY Gene - GeneCards | SRY Protein | SRY Antibody

    Nov 14, 2025 · SRY (Sex Determining Region Y) is a Protein Coding gene. Diseases associated with SRY include 46,Xx Sex Reversal 1 and 46,Xy Sex Reversal 1. Among its related pathways are …

  5. What is the SRY gene test, and should it be used to test female ...

    Aug 8, 2025 · SRY stands for sex determining region Y gene, and it’s usually found on the Y chromosome. If a human embryo has XY chromosomes, then at six weeks of development the SRY …

  6. Entry - *480000 - SEX-DETERMINING REGION Y; SRY - OMIM

    Sinclair et al. (1990) identified a gene, which they named SRY (sex-determining region Y), within a 35-kb sex-determining region on the human Y chromosome that was adjacent to the pseudoautosomal …

  7. SRY Gene - an overview | ScienceDirect Topics

    SRY: The Critical Y-Linked Testis-Determining Gene In 1990, Sinclair et al. isolated and characterized the SRY gene (sex-determining region on the Y chromosome) from the human Y chromosome and …

  8. Sex-determining Region Y in Mammals | Embryo Project Encyclopedia

    Dec 31, 2013 · The Sex-determining Region Y (Sry in mammals but SRY in humans) is a gene found on Y chromosomes that leads to the development of male phenotypes, such as testes. The Sry gene, …

  9. SRY Gene: A Comprehensive Guide to the Sex-Determining ... - Genetics

    Dec 20, 2023 · Located on the Y chromosome, the SRY gene is primarily expressed in the cells of the developing gonads. Its expression triggers a cascade of molecular events that lead to the …

  10. SRY sex determining region Y [Homo sapiens (human)] - Gene - NCBI

    Aug 19, 2025 · Gene target information for SRY - sex determining region Y (human). Find diseases associated with this biological target and compounds tested against it in bioassay experiments.